Currently, the prevention and control of COVID-19 over the world is still severe. As the first step of nucleic acid detection, the importance of specimen collection and preservation is undoubted. If there is any problem with the specimen collection, the result would be invalid even if the work is done well. Choosing the right virus transport solution can greatly improve the accuracy of the test result.
The unique non-guanidinium patented formula from Dewei could minimize the risk of "false negative" results. Almost all virus transport medium on the market now preserves the activated virus, which has a high risk of infection in sampling, transportation, and testing.
Front-line epidemic prevention workers need a preservation solution that can directly inactivate the virus. It should be considered whether the medium can stabilize the integrity of the virus RNA and avoid degradation before testing, which will cause "false negative" results.
On comparing the preservation effects of guanidinium medium with other brands and non-guanidinium solution from Dewei at 37°C on avian coronavirus, it was found that the preservation effect of the guanidinium preservation medium was unsatisfactory. On the other hand, after one to seven days of storage under the conditions of 37 ℃, the virus RNA preservation efficiency is constant at 100 per cent by using Dewei’s Virus transport solution.
While using the other two guanidinium component medium, the virus RNA preservation efficiency gradually decreases. It was reduced to less than 20 per cent after seven days, indicating RNA degradation over time. However, Dewei Medical’s preservation solution with non-guanidinium protein denaturant component can inactivate the virus and make sure the viral nucleic acid is not degraded when stored under room temperature.
Sherry Cai, Dewei Medical’s Sales Director said: “Our team has more than 20 years’ experience in the In Vitro Diagnostics (IVD) field. We provide Virus Transport Kits for Preservation and Extraction before Covid-19 PCR testing. The shelf life of the test kit is 12 months. When opened, the virus can be stored at room temperature for seven days. We offer inactivated solution to avoid the operating infection.”
The benefits of Dewei’s nucleic acid preservation kit are that the extraction of high concentration DNA & RNA will be achieved after heat treatment of the specimen. The preservation solution could be directly used for the next PCR process. Moreover, the DNA and RNA samples can be preserved without degradation within seven days at room temperature to ensure sample quality. Also, the preservation solution has no inhibition on the PCR reaction. And most importantly, it effectively inactivates pathogens, such as viruses and bacteria, without risk of biological safety.
Dewei Medical’s test kit advantages
- Completed qualification: European CE, U.S. FDA and Chinese FDA registration;
- Elegant packaging: Individual package with reagent tube and swab;
- Higher accuracy: Non-guanidine reagent;
- Safe operation: Inactivated virus solution;
- Excellent sealing of tube: Shatter-proof and exposed to freezing temperature; withstand centrifuge up to 6kg.
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